What does code 81540 cost?

Across the published hospital price files, the disclosed cash price for 81540 ranges from $4,752 to $12,656. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Will this be my final bill?

Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.

81540 is the billing code hospitals use to identify "Oncology tum unknown origin" on their published price files. We use it to line up the same service across different hospitals.

Why do prices for this code differ between hospitals?

Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.

What this page is not

It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

81540

HCPCS

Oncology tum unknown origin

Verified from hospital fileNot a bill estimate

iDirect answer

Based on the latest published hospital price files, code 81540 (Oncology tum unknown origin) appears at 12 hospitals with disclosed cash prices from $4,752 to $12,656. This is public hospital price transparency data, not a guaranteed estimate of your bill.

Published-price availability

hospitals publish a price

list this service without a published price

Cash

List

Negotiated

Allowed

A blank price (“—”) means a hospital names this service but did not publish a dollar amount — it is not a free service or a $0 price.

Compare 81540 prices

Filter by hospital, city, setting, or payer — the summary and charts update with your filters.

Based on hospital-published prices verified from each hospital’s own file. Coverage expands as data is verified.

Published cash prices for code 81540 vary by about 2.7× across the 2 hospitals with disclosed prices here — from $4,752 to $12,656. Shopping around can matter.

Hospitals

Prices shown

$4,752

Lowest cash

$12,656

Highest cash

code 81540 cash price2 disclosed · 2 hospitals

$4,752median ~$8,704$12,656

Lowest cash price by hospital

Cash price by city

Reflects your current filters.

Cash price by city$4,752 – $12,656

Polson · 1 hospital$4,752
New York · 1 hospital$12,656

12 prices shown.

Service	Hospital	Code	List price	Cash price	Negotiated range	Allowed (median)
Oncology tum unknown origin Outpatient	Endeavor Health Edward Hospital	81540 HCPCS	—	—	$3,750 – $6,353	—
Oncology tum unknown origin Outpatient	University of Chicago Medical Center	81540 HCPCS	—	—	—	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	Aurora Medical Center Burlington	81540 CPT	—	—	$3,000 – $13,161	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	Aurora Medical Center Bay Area	81540 CPT	—	—	$3,000 – $13,161	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	Aurora Medical Center Fond du Lac	81540 CPT	—	—	$3,000 – $13,161	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	The Women's Hospital	81540 CPT	—	—	$1,500 – $9,188	—
HC ONCOLOGY TUM UNKNOWN ORIGIN Inpatient & outpatient	Providence St Joseph Medical Center	81540 HCPCS	$5,940	$4,752	—	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	University Hospitals Cleveland Medical Center	81540 CPT	—	—	$3,750 – $6,750	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	University Hospitals Ahuja Medical Center	81540 CPT	—	—	$3,750 – $9,000	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	University Hospitals Elyria Medical Center	81540 CPT	—	—	$3,750 – $9,000	—
Oncology (tumor of unknown origin), mRNA, gene expression profiling by real-time RT-PCR of 92 genes (87 content and 5 housekeeping) to classify tumor into main cancer type and subtype, utilizing formalin-fixed paraffin-embedded tissue, algorithm reported as a probability of a predicted main cancer t Outpatient	University Hospitals Regional Hospitals - Geauga Medical Center	81540 CPT	—	—	$3,750 – $9,000	—
ONCOLOGY TUM UNKNOWN ORIGIN - Inpatient & outpatient	New York Eye and Ear Infirmary of Mount Sinai	81540 HCPCS	$14,063	$12,656	—	—

How to read these prices

Cash price: The discounted self-pay price for paying directly, without insurance.
List price: The hospital’s full undiscounted charge — rarely what anyone pays.
Negotiated rate: A rate for a specific insurer and plan; your share depends on your benefits.
Allowed amount: A historical reference for what was actually allowed, where disclosed.

Hospitals that publish 81540 prices

Open a hospital to see this code in the context of its full published prices.

Endeavor Health Edward Hospital University of Chicago Medical Center Aurora Medical Center Burlington Aurora Medical Center Bay Area Aurora Medical Center Fond du Lac The Women's Hospital Providence St Joseph Medical Center University Hospitals Cleveland Medical Center University Hospitals Ahuja Medical Center University Hospitals Elyria Medical Center University Hospitals Regional Hospitals - Geauga Medical Center New York Eye and Ear Infirmary of Mount Sinai

Code 81540: frequently asked

What does code 81540 cost?: Across the published hospital price files, the disclosed cash price for 81540 ranges from $4,752 to $12,656. This is public hospital price transparency data, not a guaranteed estimate of your bill.
Will this be my final bill?: Actual patient responsibility may vary based on your insurance plan, deductible, coinsurance, network status, diagnosis, setting, bundled services, clinical circumstances, and hospital billing practices.
What is code 81540?: 81540 is the billing code hospitals use to identify "Oncology tum unknown origin" on their published price files. We use it to line up the same service across different hospitals.
Why do prices for this code differ between hospitals?: Each hospital sets its own prices and negotiates separately with each insurer, so the disclosed price for the same code can vary widely from one hospital to another — and even between plans at a single hospital. Comparing the published figures is what this page is for; a difference does not by itself mean one hospital is better or worse.
What this page is not: It is not a quote, a guarantee, or medical advice. It shows what hospitals have published for this code, so you can compare and ask informed questions — your actual cost depends on your insurance, the exact services performed, and the care setting.

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